Pargyline hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

盐酸帕吉林是一种不可逆的单胺氧化酶（MAO）抑制剂，临床上用于治疗中度高血压。

Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension.

Cell Proliferation Assay Cell Line:LNCaP-LN3 cells Concentration:0.5 mM, 1 mM, 1.5 mM or 2 mM Incubation Time:24 hours, 48 hours, 72 hours, 96 hours or 120 hours Result:Inhibited the proliferation of prostate cancer cells in a time- and dose-dependent manner.Cell Cycle Analysis Cell Line:LNCaP-LN3 cells Concentration:0.5 mM, 2 mM Incubation Time:24 hours, 48 hours Result:The S phase ratio of the cells was decreased, while their G1 phase ratio was increased.Apoptosis Analysis Cell Line:LNCaP-LN3 cells Concentration:0.5 mMIncubation Time:24 hours Result:Increased the apoptotic cells.Western Blot Analysis Cell Line:LNCaP-LN3 cells Concentration:2 mM Incubation Time:48 hours Result:Induced an increase of cytochrome c and a decrease of caspase-3.

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NSC 43798

Metabolic Enzyme/Protease

MAO

MAO

Neurological Disease

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306-07-0

195.69

C11H14NCl

>98% (HPLC)

DMSO: 38 mg/mL

CN(CC#C)CC1=CC=CC=C1.Cl

N-benzyl-N-methylprop-2-yn-1-amine;hydrochloride

(-20℃)

With Ice Pack

≥ 2 years